GHK-CU 10,000mg
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GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. Consisting of 3 amino acids, this synthetic formulation is heavily researched for its high affinity for copper(II) ions and its role in extracellular matrix remodeling. In laboratory settings, GHK-Cu is investigated for its potential to stimulate collagen and elastin synthesis, as well as its modulatory effects on tissue repair and cellular antioxidant defense mechanisms.
For Research Use Only. Not for human consumption.
$1,395.00
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In stock
GHK-Cu possesses the molecular formula C₁₄H₂₄CuN₆O₄. It is a specific sequence of three amino acids (Gly-His-Lys) that acts as a strong coordinating ligand for copper ions. Naturally found in human plasma, saliva, and urine, endogenous levels of this complex have been observed to decline significantly with age. In experimental environments, the synthetic form of GHK-Cu is utilized to study the localized effects of targeted copper delivery on cellular function and gene expression without systemic variables.
Scientific studies focus predominantly on the interaction between GHK-Cu and dermal fibroblasts. Research indicates that the peptide may influence the upregulation of vital structural proteins, including collagen type I and III, elastin, and various glycosaminoglycans. Furthermore, GHK-Cu is investigated in isolated cell cultures for its ability to modulate the activity of both matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), balancing the breakdown and deposition of the extracellular matrix.
Investigators also explore the capacity of GHK-Cu to exhibit antioxidant and anti-inflammatory properties in vitro. By evaluating its impact on reactive oxygen species (ROS) and the secretion of inflammatory cytokines, researchers hypothesize that the peptide protects cellular DNA from oxidative damage. This mechanism is frequently utilized to study enhanced nutrient delivery, angiogenesis, and structural support in experimental models of dermal repair, tissue remodeling, and cellular aging.
This product is strictly for laboratory and research purposes only. GHK-Cu is not intended for human use, diagnostic, or therapeutic procedures. It serves as a reagent for scientific study and method development.
References
- Pickart, L., et al. (2015). “GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration.” BioMed Research International, 2015, 648108.
- Pickart, L., & Margolina, A. (2018). “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.” International Journal of Molecular Sciences, 19(7), 1987.
- Maquart, F. X., et al. (1988). “Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+.” FEBS Letters, 238(2), 343-346.
