Buy Retatrutide GLP1R – GLP3 – Mannitol-Free Research Peptide
Choose Standard Batch for stable inventory or Fresh Microbatch for recent small-run production, finalized within the last 1–3 weeks to preserve maximum available peptide content – never warehouse stock.
Buy Retatrutide (LY3437943) – Research Vials 10–30 mg
BulkGLP supplies Retatrutide as mannitol-free, lyophilized research vials for qualified laboratories. All formats meet the same analytical specification (≥99% purity, third-party HPLC/MS). Standard Batch inventory includes a current COA on this page; Fresh Microbatch offers a per-batch COA by verified request.
Laboratory Research Use Only. Not for human or veterinary use. No clinical, diagnostic, or therapeutic claims are made or implied.
Available Batch Formats
Standard Research Batch
- ≥99% purity (HPLC/MS) – COA on page
- Cold-stored for stability and planning simplicity
- Singles **and** 10-packs (lot-consistent where possible) for method development
- Best value for routine, repeatable research workflows
Fresh Microbatch Retatrutide: (Premium)
- Purity Verified: Manufactured and lab-certified within the last 3 weeks, ensuring the highest level of **freshness, integrity, and potency**.
- Superior Chain-of-Custody: Optimized, rapid supply chain with enhanced handling protocols to maintain **molecular stability** from synthesis to your lab.
- Exclusive Availability: Controlled, small-run batches (singles only)
- Full Transparency: Dedicated **Certificate of Analysis (COA)**
Pricing note: Fresh Microbatch reflects a premium tier due to limited release volume, small-run handling, and shorter time-to-finalization. Standard Batch retains identical analytical specifications and remains the best value for routine studies.
What Is Retatrutide (LY3437943)?
Retatrutide is a triple-agonist peptide investigated for concurrent engagement of GLP-1, GIP, and glucagon receptors. In preclinical and early clinical research, triple agonism has been explored to combine appetite-related signaling, incretin-driven insulinotropic effects, and energy-expenditure pathways within a single molecule.
- GLP-1 receptor — satiety signaling, gastric emptying, glycemic control
- GIP receptor — glucose-dependent insulin secretion and complementary incretin signaling
- Glucagon receptor — hepatic lipid metabolism and thermogenic/energy-expenditure signals
Supplied for in-vitro/ex-vivo research by qualified laboratories; not for administration to humans or animals.
Mechanistic Overview
- GLP-1 axis: satiety and post-prandial glucose dynamics
- GIP axis: potentiates glucose-dependent insulin secretion
- Glucagon axis: lipid mobilization and thermogenic signaling; balanced activation is a key study variable
Research Evidence Snapshot
Published reports (preclinical and Phase 2) have described notable body-weight endpoints and metabolic markers with triple-agonist designs compared with single/dual incretin approaches, alongside tolerability profiles consistent with incretin-pathway agents. Teams should review the primary literature for detailed methods, inclusion criteria, titration paradigms, and endpoint definitions.
Retatrutide vs Tirzepatide vs Semaglutide
| Feature | Retatrutide | Tirzepatide | Semaglutide |
|---|---|---|---|
| Agonism | Triple: GLP-1, GIP, Glucagon | Dual: GLP-1, GIP | Single: GLP-1 |
| Research Focus | Combined appetite, glycemic & energy-expenditure pathways | Incretin synergy; appetite & glycemic control | Satiety signaling & glycemic control |
| Design Notes | Balance of glucagon activity for lipid/thermogenic endpoints | Nausea management & titration often evaluated | Well-characterized GLP-1 profile |
Why BulkGLP
- Analytical Grade: ≥99% purity by third-party HPLC/MS
- Mannitol-Free: No bulking agents or buffers — pure lyophilized peptide
- Two Batch Formats:Standard: Cold-stored ≤90 days; value-forward; COA on page; singles and 10-packs.Fresh Microbatch: Finalized within ~1–3 weeks; small-run handling; per-batch COA by request; singles only.
- Lot Consistency: Standard 10-packs drawn from the same controlled lot where possible
- U.S. Fulfillment: Discreet, trackable shipments with temperature-appropriate packing as needed
Format & Handling
- Form: Lyophilized peptide in sealed, sterile research vials (13 mm stopper/crimp)
- Fill Amounts: 10 mg, 15 mg, 20 mg, 30 mg per vial
- Reconstitution (General Lab Practice): Introduce bacteriostatic water or suitable research-grade solvent down the vial wall; allow to wet, then gently swirl. Avoid vigorous agitation/foaming. Record final concentration in your ELN.
- Calculator: Use the BulkGLP Peptide Calculator to derive mg/mL targets and aliquot volumes for your protocol.
Product Specifications
- Name: Retatrutide
- Synonyms: LY3437943
- Purity: ≥99% (HPLC/MS, third-party)
- Appearance: White/off-white lyophilized powder
- Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
- Molecular Weight: ~4,731.33 g/mol
- Additives: None (mannitol-free; no buffers/excipients)
- Intended Use: In-vitro/ex-vivo laboratory research only
Storage & Stability
- Unreconstituted: Store in a dry, light-protected environment
- After Reconstitution: 2–8 °C; aliquot to minimize freeze–thaw cycles; follow sterility SOPs
- Shelf Life: 4 years
Frequently Asked Questions
What is “Fresh Microbatch”?
A premium release format produced in small runs and finalized within approximately 1–3 weeks of site availability. It emphasizes shorter supply-chain timelines and enhanced handling/chain-of-custody. Per-batch COA is available upon verified request. Singles only.
Is Fresh Microbatch a different purity than Standard?
No. Both formats meet the same analytical specification (≥99% purity, third-party HPLC/MS). The difference is production cadence, handling, and release format — not the stated analytical spec.
Why are there no 10-packs for Fresh Microbatch?
To maintain availability across labs and preserve small-run release cadence, Microbatch is offered as singles only. Standard Batch supports 10-packs for lot-consistent study replicates and cost efficiency.
How often is Fresh Microbatch available?
Availability varies with production cadence. Microbatch lots are released on a limited basis; when a lot sells out, the next allocation is released during the subsequent cycle. Standard inventory remains available for routine planning.
Is Retatrutide the “GLP-3” peptide?
“GLP-3” is informal shorthand used online. Retatrutide (LY3437943) is more precisely a triple agonist of GLP-1, GIP, and glucagon receptors.
What solvent should I use for reconstitution?
Many labs use bacteriostatic water for convenience in handling and storage. Follow your internal SOP and maintain aseptic technique.
Legal & Safety
All products are supplied for laboratory research use only. Not for human or veterinary administration. End users are responsible for compliance with applicable laws and institutional policies. By purchasing, you acknowledge these terms.
| Weight | 0.1 lbs |
|---|---|
| Dimensions | 2 × 2 × 2 in |
| Size | 5mg, 10mg, 15mg, 20mg, 30mg, 5mg – 10 Pack, 10mg – 10 Pack, 15mg – 10 Pack, 20mg – 10 Pack, 30mg – 10 Pack |
| Product Grade | Standard Batch, Fresh Microbatch (Recommended) 🔥 |
2 reviews for Buy Retatrutide GLP1R - GLP3 - Mannitol-Free Research Peptide
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Katy –
Observations in my research have been impressive so far. The compound appears to strongly influence appetite-related pathways and significantly reduce cravings in testing environments, even during periods when cravings are typically elevated. After about 30 days of consistent research, measurable progress was recorded. Very satisfied with the quality and purity of this Retatutrid and will continue future research.
Raptor14 –
Excellent quality compound. Unlike others I’ve tested, this one delivers consistent results without any unexpected issues during research. Very satisfied with the purity and overall experience will continue future research projects with this supplier.