AHK-CU 10,000mg
Free Priority Shipping on Orders $99+
AHK-Cu is a synthetic copper-binding tripeptide consisting of the amino acid sequence Alanine-Histidine-Lysine. Research investigates this compound for its potential to stimulate fibroblast proliferation and modulate the expression of vascular endothelial growth factor (VEGF). In laboratory models, it is frequently studied for its role in cellular signaling pathways related to dermal extracellular matrix remodeling and hair follicle development.
For Research Use Only. Not for human consumption.
$1,253.00
In stock
In stock
AHK-Cu possesses the molecular formula C₁₅H₂₄CuN₆O₄. It is a specific sequence of three amino acids (Ala-His-Lys) complexed with a copper (II) ion. This tripeptide shares structural similarities with the well-known GHK-Cu peptide but is distinguished by the substitution of glycine with alanine at the N-terminus. In laboratory environments, the synthetic version is utilized to isolate its specific biological activities, with the copper ion acting as a crucial cofactor in various enzymatic processes.
Scientific studies focus predominantly on the interaction between AHK-Cu and dermal fibroblasts as well as dermal papilla cells. Research indicates that the peptide may promote the survival and proliferation of these cells, while simultaneously upregulating the synthesis of collagen type I. Furthermore, AHK-Cu is widely investigated in isolated cell cultures for its potential to delay the apoptosis of dermal papilla cells, providing a model for understanding the mechanisms that extend the anagen (growth) phase of hair follicles.
Investigators also explore the capacity of AHK-Cu to stimulate localized angiogenesis. By evaluating the secretion of vascular endothelial growth factor (VEGF) from cellular models, researchers hypothesize that the peptide improves microcirculation within the surrounding tissue matrix. This mechanism is frequently utilized to study enhanced nutrient delivery and structural support in experimental models of tissue repair and cellular aging.
This product is strictly for laboratory and research purposes only. AHK-Cu is not intended for human use, diagnostic, or therapeutic procedures. It serves as a reagent for scientific study and method development.
References
- Pyo, H. K., et al. (2007). “The effect of tripeptide-copper complex on human hair growth in vitro.” Archives of Pharmacal Research, 30(7), 834-839.
- Kang, Y. A., et al. (2009). “Copper-AHK promotes hair growth through the down regulation of transforming growth factor-beta1 in dermal papilla cells.” Annals of Dermatology, 21(2), 142-148.
- Pickart, L., & Margolina, A. (2018). “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.” International Journal of Molecular Sciences, 19(7), 1987.
