VIP

VIP

Free Priority Shipping on Orders $99+

VIP (Vasoactive Intestinal Peptide) is a synthetic 28-amino acid neuropeptide that functions as a widespread neurotransmitter and neuromodulator. Research investigates its high affinity for VPAC1 and VPAC2 receptors, exploring its role in smooth muscle relaxation, systemic vasodilation, and the modulation of neuroendocrine-immune network pathways in laboratory models.

For Research Use Only. Not for human consumption.

$74.00

In stock

In stock

Category:

VIP possesses the molecular formula C₁₄₇H₂₃₈N₄₂O₄₃. Structurally, it is a linear polypeptide consisting of 28 amino acids and belongs to the glucagon/secretin superfamily of peptides. In biological systems, the endogenous hormone acts via two primary G-protein-coupled receptors, designated VPAC1 and VPAC2. Laboratory synthesized VIP is utilized to examine these receptor interactions and the subsequent activation of the adenylate cyclase-cAMP signaling cascade.

Scientific studies focus heavily on the peptide’s potent vasodilatory and bronchodilatory effects. In in vitro assays and animal models, researchers observe how the administration of VIP influences the relaxation of smooth muscle tissues, particularly within the gastrointestinal tract and pulmonary system. This mechanism provides a crucial framework for studying altered vascular resistance and blood flow dynamics under controlled experimental conditions.

Beyond its hemodynamic properties, VIP is extensively investigated for its immunomodulatory and neuroprotective potential. Research indicates that the peptide may downregulate pro-inflammatory cytokines, such as TNF-alpha and IL-6, while promoting the release of anti-inflammatory mediators. Additionally, it is studied for its role in maintaining the circadian rhythm within the suprachiasmatic nucleus. Investigators utilize this molecule to understand the complex neuro-immune axis and cellular survival pathways during induced inflammatory stress.

This product is strictly for laboratory and research purposes only. VIP is not intended for human use, diagnostic, or therapeutic procedures. It serves as a reagent for scientific study and method development.

References

  1. Delgado, M., et al. (2004). “Vasoactive intestinal peptide: neuromodulator and immune regulator.” Trends in Neurosciences, 27(10), 615-623.
  2. Henning, R. J., & Sawmiller, D. R. (2001). “Vasoactive intestinal peptide: cardiovascular effects.” Cardiovascular Research, 49(1), 27-37.
  3. Brenneman, D. E. (2007). “Neuroprotection: a comparative view of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide.” Peptides, 28(9), 1720-1726.

Related products

Get 10% Off Your Order!

Join our list and get an instant discount code.

You're In!

Use this code at checkout:

Get 10% Off
Get 10% Off
0

Terms & Conditions

Last updated: September 23, 2025

These Terms & Conditions (“Terms”) govern your use of bulkglp.com and your purchase/use of our products and services (the “Services”). By using the Services, you agree to these Terms.

1. Research Use Only

All products are intended strictly for laboratory research by qualified individuals/entities. Products are not for human or veterinary use, ingestion, injection, diagnostic, therapeutic, or household use.

2. Eligibility & Compliance

  • You are at least 18 years old (or older where required) and legally able to enter contracts.
  • You purchase for legitimate research and will comply with applicable laws/regulations.
  • You will follow appropriate lab safety, handling, storage, and disposal protocols.

3. Research-Use Certification

By ordering, you certify you understand hazards/handling, are qualified to use these materials, will not use them for human/animal applications, and will not resell in violation of these Terms or law.

4. No Medical Advice; No FDA Evaluation

Site content is for research/educational purposes only. Statements are not evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

5. Orders, Pricing, Availability

  • Orders are offers to buy; acceptance occurs when we dispatch goods.
  • Prices/descriptions/availability may change without notice; errors may be corrected at any time.
  • We may impose quantity limits or require additional verification prior to shipment.

6. Payment & Fraud

You authorize charges to your selected payment method, including shipping and taxes. We use risk tools and may request additional information; unverifiable orders may be canceled.

7. Shipping, Risk of Loss, Customs

Title and risk of loss transfer upon carrier acceptance. Inspect upon delivery and retain materials for any claim. Delivery estimates are not guarantees; carrier delays are outside our control. International buyers are responsible for import compliance, duties, and taxes.

8. Returns & Refunds

See our Refund Policy. Due to sterility and chain-of-custody, reconstituted, opened, or punctured vials cannot be returned or refunded.

9. Product Handling, Safety & COAs

Products may pose hazards if mishandled. Use only in controlled lab environments with appropriate PPE. Certificates of Analysis (COAs) may be provided on the Site or with products.

10. Intellectual Property

All Site content (text, graphics, logos, images, data, and code) is owned by BulkGLP or its licensors. You may not copy, modify, distribute, or create derivative works without prior written consent.

11. Acceptable Use

No scraping, reverse engineering, security probing, spam, or interference. No use that violates laws, infringes rights, or facilitates illegal activity.

12. Disclaimers

TO THE MAXIMUM EXTENT PERMITTED BY LAW, THE SERVICES AND PRODUCTS ARE PROVIDED “AS IS” AND “AS AVAILABLE,” WITHOUT WARRANTIES OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, AND NON-INFRINGEMENT. RESEARCH MATERIALS MAY BE EXPERIMENTAL AND INVOLVE RISKS.

13. Limitation of Liability

TO THE MAXIMUM EXTENT PERMITTED BY LAW, BULKGLP AND ITS OFFICERS, DIRECTORS, EMPLOYEES, AND AGENTS WILL NOT BE LIABLE FOR INDIRECT, INCIDENTAL, SPECIAL, CONSEQUENTIAL, EXEMPLARY, OR PUNITIVE DAMAGES, OR ANY LOSS OF PROFITS, REVENUE, DATA, OR GOODWILL. OUR TOTAL LIABILITY FOR ANY CLAIM WILL NOT EXCEED THE AMOUNT YOU PAID FOR THE PRODUCT AT ISSUE.

14. Indemnification

You agree to indemnify and hold harmless BulkGLP from claims, losses, liabilities, damages, costs, and expenses (including reasonable attorneys’ fees) arising out of your use/misuse of products or the Services, your violation of these Terms, or any law/right of a third party.

15. Dispute Resolution; Arbitration; Class-Action Waiver

  • Governing Law: Texas law (without regard to conflicts principles).
  • Arbitration: Any dispute relating to these Terms or the products will be resolved by binding arbitration in Dallas County, Texas. Judgment on the award may be entered in any court of competent jurisdiction.
  • Class-Action Waiver: Disputes must be brought individually, not as a class or representative action.

16. Changes

We may update these Terms at any time. The “Last updated” date reflects the latest version. Continued use after changes are effective constitutes acceptance.

17. Contact

For questions regarding these Terms, contact us:
Email: support@bulkglp.com
Postal: BulkGLP, Dallas, TX, USA